Up to 85% of people who are infected with the
hepatitis C virus will develop long-term (chronic)
infection.1 About 25% of people who have chronic
hepatitis C will go on to develop
cirrhosis—severe liver damage and scarring—after a
period of about 20 years or more.2
Certain factors may affect how quickly problems such as cirrhosis or
liver cancer develop.
The way cirrhosis develops depends on:3
CitationsDienstag JL (2010). Chronic viral hepatitis. In GL
Mandell et al., eds., Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7th ed., vol. 1, pp.
1593–1670. Philadelphia: Churchill Livingstone Elsevier.Flamm SL (2003). Chronic hepatitis C virus infection.
JAMA, 289(18): 2413–2417.Poynard T, et al. (2003). Viral hepatitis C.
Lancet, 362(9401): 2095–2100.
July 6, 2011
E. Gregory Thompson, MD - Internal Medicine & W. Thomas London, MD - Hepatology
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