What is dalfampridine?
Dalfampridine is a potassium channel blocker.
Dalfampridine is used to improve walking in patients with multiple sclerosis (MS).
Dalfampridine may also be used for purposes not listed in this medication guide.
How should I take dalfampridine?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Dalfampridine is usually taken once every 12 hours. Follow your doctor's instructions.
 | Do not take more than 2 tablets in a 24-hour period. |
Dalfampridine may be taken with or without food.
 | Do not crush, chew, or break an extended-release tablet. Swallow it whole. Do not dissolve the tablet in liquid. Breaking or dissolving the pill may cause too much of the drug to be released at one time. |
 | Do not use a dalfampridine tablet that has been accidentally crushed or broken. This can increase your risk of having a seizure. |
 | Store at room temperature away from moisture and heat. |
Throw away any leftover medicine after the expiration date on the label has passed.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
| Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. |
Overdose can cause confusion, problems with thinking or memory, tremors, sweating, or seizures.
What should I avoid while taking dalfampridine?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What are the possible side effects of dalfampridine?
| Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. |
| Stop taking dalfampridine and call your doctor at once if you have a serious side effect such as: |
- seizure (convulsions);
- pain or burning when you urinate;
- problems with balance;
- numbness, burning pain, or tingly feeling;
- relapse or worsening of MS symptoms;
Less serious side effects may include:
- headache, dizziness;
- sleep problems (insomnia);
- nausea, constipation, upset stomach;
- weakness;
- stuffy nose, sinus pain, sore throat; or
- back pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect dalfampridine?
There may be other drugs that can interact with dalfampridine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about dalfampridine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 3.01. Revision date: 11/9/2011.
Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by
clicking on this link.