Wild yam and progesterone creams are available without a prescription
and are marketed for relieving
Wild yam. Although wild yam cream is marketed
as a source of natural progesterone, it does not contain progesterone, and the
body cannot convert it into progesterone.1
Progesterone creams. Some women use "natural"
progesterone creams to correct low progesterone levels. Research is mixed about
whether the cream is absorbed into the body.
You can't actually know how much progesterone you are getting
without having a whole-blood progesterone test. Because of this and the
following concerns, some experts are concerned about use of over-the-counter
CitationsAmerican College of Obstetricians and Gynecologists
(2001, reaffirmed 2008). Use of botanicals for management of menopausal
symptoms. ACOG Practice Bulletin No. 28. Obstetrics and Gynecology, 97(6, Suppl): 1–11.Hermann AC, et al. (2005). Over-the-counter
progesterone cream produces significant drug exposure compared to a Food and
Drug Administration-approved oral progesterone product. Journal of Clinical Pharmacology, 45(6): 614–619.
April 26, 2012
Anne C. Poinier, MD - Internal Medicine & Carla J. Herman, MD, MPH - Geriatric Medicine
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