Selective serotonin reuptake inhibitors (SSRIs) balance
brain chemicals called
neurotransmitters. Balancing these brain chemicals can
relieve symptoms of
borderline personality disorder such as irritability,
anger, impulsive behavior, and depression.
Some examples of SSRIs
that may be used to treat borderline personality disorder are:
SSRIs are often the first medicine used to treat borderline
personality disorder, because they often are effective and have few side
Side effects of selective
serotonin reuptake inhibitors include:
SSRIs can take several weeks to start working, although they
may be effective sooner.
Never suddenly stop taking antidepressants. Many antidepressants should be tapered off
slowly and only under the supervision of a doctor. Abruptly stopping
antidepressant medicines can cause negative side effects or a return of
symptoms of borderline personality disorder.
FDA Advisories. The U.S. Food and Drug Administration (FDA) has
CitationsAmerican Psychiatric Association (2001). Practice
guidelines for the treatment of patients with borderline personality disorder.
American Journal of Psychiatry, 158(10): 1–52.
March 14, 2011
Sarah Marshall, MD - Family Medicine & Lisa S. Weinstock, MD - Psychiatry
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