Examples
|
| medroxyprogesterone | Provera |
| megestrol | Megace |
How It Works
A woman's body makes the hormone
progesterone.
Progestin is the man-made form of progesterone.
It is usually given in pill
form.
Hormone therapy works by blocking the action of hormones and stopping cancer cells from growing.
Why It Is Used
Progestin hormone therapy may be used to slow the growth of
endometrial cancer. This may be done when the cancer has spread to other parts of the body. Or it may be done for a young woman with early-stage cancer so she can become pregnant in the future.
How Well It Works
Progestin hormone therapy has been shown to slow cancer cell growth for up to 30% of women
who had advanced endometrial cancer. This therapy also helped to slow
cancer cell growth in women who had endometrial cancer that had come back after treatment.1
Side Effects
Progestin hormone therapy can cause side effects, including:
- Nausea or
vomiting.
- Dizziness.
- Mild shortness of
breath.
- Weakness.
- Headache.
- Hot flashes or
sweating.
- Decreased sex drive.
- Insomnia.
Serious side effects are rare but may include:
- An
allergic reaction.
- Sudden severe
headache.
- Changes in eyesight.
- Numbness or swelling in
an arm or leg.
Progestin hormone therapy is also used as an appetite stimulant.
You may experience an increased appetite, which could result in weight
gain.
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
What To Think About
Progestin hormone therapy may be given to women who are unable to
have surgery or radiation therapy.
Women who have endometrial cancer that has spread to other parts
of the body may live longer if they receive progestin
hormone therapy.1
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
References
Citations
- National Cancer Institute (2012). Endometrial Cancer Treatment (PDQ)—Health Professional Version. Available online: http://www.cancer.gov/cancertopics/pdq/treatment/endometrial/HealthProfessional.
Credits
| By | Healthwise Staff |
|---|
| Primary Medical Reviewer | Sarah Marshall, MD - Family Medicine |
|---|
| Specialist Medical Reviewer | Ross Berkowitz, MD - Obstetrics and Gynecology |
|---|
| Last Revised | November 29, 2010 |
|---|
Last Revised:
November 29, 2010
National Cancer Institute (2012). Endometrial Cancer Treatment (PDQ)—Health Professional Version. Available online: http://www.cancer.gov/cancertopics/pdq/treatment/endometrial/HealthProfessional.