Cyclosporine ophthalmic eyedrops usually are applied twice
a day, or as directed by your doctor.
Cyclosporine is an immunosuppressive
medicine that decreases the action of your body's
immune system. Cyclosporine ophthalmic is used in
eyedrop form to treat
Sjögren's syndrome, a disease that causes dry eyes and
Sjögren's syndrome is an
autoimmune disorder in which the immune system attacks
the body's moisture-producing glands and may eventually cause problems with the
function of vital organs, such as the lungs, bladder, kidneys, and liver.
Cyclosporine reduces the immune system's action in the glands that moisten the
eyes and may reduce eye
Studies report that cyclosporine
ophthalmic may increase tear production, relieve blurred
vision, and decrease the use of artificial tears.1
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
Call 911 or other emergency services right away if you have:
Call your doctor if you have:
Common side effects of this medicine include:
See Drug Reference for a full list of side effects. (Drug Reference is
not available in all systems.)
Do not apply cyclosporine
ophthalmic medicine while wearing contact lenses. After you apply cyclosporine,
wait at least 15 minutes, or as long as is advised by your doctor, to insert
To prevent eye infection, use the solution from the single-use vial immediately after you open it, and throw away anything remaining in the vial. Be careful not to
contaminate the stopper by touching it to any surface, including your eyes,
your hands, the sink, or the countertop.
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
If you are pregnant, breast-feeding, or planning to get pregnant, do not use any medicines unless your doctor tells you to. Some medicines can harm your baby. This includes prescription and over-the-counter medicines, vitamins, herbs, and supplements. And make sure that all your doctors know that you are pregnant, breast-feeding, or planning to get pregnant.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
Citations Ophthalmic cyclosporine (Restatis) for dry eye
disease (2003). Medical Letter on Drugs and Therapeutics, 45(W1157B): 42–43.
April 27, 2012
Adam Husney, MD - Family Medicine & E. Gregory Thompson, MD - Internal Medicine
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