Intermountain Heart Institute at Intermountain Medical Center

(801) 507-4701Map5121 S. Cottonwood StreetMurray, UT 84107

Our lab focuses on the study of biomarkers (such as DNA mutations and blood proteins) and their relationship to cardiovascular and other diseases. We have supported numerous studies funded by the National Institutes of Health and the American Heart Association. The laboratory is staffed by a director, John Carlquist, PhD, four laboratory technicians who are trained to develop and perform molecular biological testing, and a core group of student volunteers.

DNA Bank

Twenty years ago, our team began collecting DNA from cardiac patients and searching for the inherited, genetic factors that underlie heart disease. Now, our lab is home to one of the world's largest cardiovascular DNA and plasma banks, which includes samples from more than 27,000 patients. Samples are maintained in -80ºC freezers for ongoing studies investigating the causes of heart disease.

Next Generation DNA Sequencer

Our next generation genetic DNA sequencer is a new, more powerful model of genetic research that allows us to sequence every possible mutation in a gene, in a rapid and cost-effective manner. The sequencer will accelerate the development of personalized medicine for our patients with cardiovascular disease.

Intermountain Heart Collaborative Study

Much is already known about the relationships between heart disease and smoking, high blood pressure, high cholesterol, and diabetes. However, scientists are still trying to discover the exact role of genetics and other biological influences on how this disease progresses.

Over the past 17 years, we have collected more than 27,000 DNA samples from patients who have been evaluated for heart disease at LDS Hospital and Intermountain Medical Center. We call it the Intermountain Heart Collaborative Study – a tremendous resource for discovering the underlying factors of heart disease.

We are continuing to expand and increase our enrollment into this important registry. Over the past three years alone, the use of this registry has resulted in the publication of more than 40 research papers, all of which were published in major international scientific journals. All patients who are 18 years of age or older and enter the cardiac catheterization lab at Intermountain Medical Center are eligible to participate. This is our own original research and there is no corporate sponsorship.

For More Information: (801) 507-4701

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