Intermountain Healthcare is at the forefront in researching new techniques and technologies in fighting heart disease. This experience leads to expertise in providing the most advanced treatment plans and better care options.

Current Research

Intermountain is nationally recognized for medical science contributions through healthcare related research that improves patient treatment methods and results in new clinical techniques.

Factor 64

A study for high risk diabetic patients using CT Angiography to help evaluate cardiovascular risk and prevent heart attacks. Patients will be randomized to standard diabetic management or will receive a CT angiogram to evaluate cardiovascular disease. Patients undergoing CT Angiography will then be placed in different groups depending on the result of the scanning.

Couma-Gen

Anticoagulation with warfarin (CoumadinÒ) is a common and potentially hazardous therapeutic intervention. It is a leading cause of iatrogenic bleeding events and, hence, of malpractice claims. There are no good alternatives presently for warfarin anticoagulation, and even when alternatives become available (i.e., ximelagatran), cost, labeling, and experience (outcomes-related) issues will continue to favor an extensive and ongoing use of warfarin.

If the present study is able to confirm an advantage for a genotype-driven algorithm, in terms of improved efficiency, therapeutic efficacy, and, especially, safety, then a pharmacogenetics approach to warfarin dosing can be recommended as the basis for a system wide quality improvement initiative that should improve patient outcomes, reduce resource use (costs of achieving safe and therapeutic anticoagulation), and reduce adverse clinical events.

Artificial Heart Research - HeartMate II Trials

These trials will determine the benefits of the HeartMate II left ventricular assist device for Bridge-to-Transplant and Permanent ("Destination") Therapy in patients with advanced heart failure. As of November 2007, the UAHP has implanted 28 patients with the HeartMate II. The results of these trials will be submitted for FDA approval.

Additional Cardiovascular Research

Intermountain's Cardiovascular Clinical Program continually seeks to improve care, conduct investigational research, discover better treatment options, and implement clinical advances.

 
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