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Atrial Septal Defect (ASD) and Patent Foramen Ovale (PFO) Closure
An Atrial Septal Defect, or ASD, is an abnormal hole in the wall of the upper chambers of the heart. This hole means the wall between the right and left upper chambers does not close completely.
Fetuses have an opening (called a foramen ovale) between the upper chambers of the heart that closes naturally soon after birth. If this fails to happen, the result is an open (patent) foramen ovale, or PFO. For either an ASD or a PFO, a cardiac cath lab procedure can be used to close the hole.
How it’s done:
Heart Transplant
A heart transplant replaces a severely diseased or malformed heart with a new heart from a human organ donor. This procedure is considered for late-stage heart failure after other attempts have failed. Transplantation is a treatment, not a cure, for heart failure. When it is successful, it offers an average 9 years of additional life.
Heart transplantation is an open heart surgery that lasts 4 to 6 hours. During the surgery, a heart-lung bypass machine takes over the work of the heart and lungs. Once the new heart is positioned in the chest and surgically attached to the major vessels, it usually begins to beat on its own and the heart-lung machine can be detached.
Patients considering transplantation should keep in mind that surgery is only one step in the process. Major steps to consider include:
Septal Ablation
Septal ablation is used when the septum (wall) that divides the lower chambers of the heart becomes abnormally thick—the procedure corrects the obstruction so that the blood can flow more freely in the heart. In this cardiac cath lab procedure, alcohol is injected into the arteries that feed the septum. This thins the septum, so the heart can work more efficiently.
Ventricular Assist Devices
PVAD
A percutaneous ventricular assist device (PVAD) is a small mechanical pump that provides short-term support for the heart from a few hours up to 15 days. It is typically used to give the heart time to strengthen if a patient has developed heart failure as a result of heart surgery or a heart attack. The PVAD is worn outside the body, and connected to the heart through a vein in the thigh. One benefit of the PVAD is that it can be inserted in the cardiac cath lab.
Left Ventricular Assist Device (LVAD)
A left ventricular assist device (LVAD) treats heart failure by easing the heart’s workload. An LVAD is a mechanical pump that assumes the work of the left ventricle, the heart’s most important pumping chamber. This allows the heart to rest, while simultaneously supporting the body with normal—or near normal—blood flow. Implanting this device requires open heart surgery.
Levitronix Ventrimag
The Levitronix Centrimag is a blood pump that can support the heart or take over the work of the heart during heart surgeries such as cardiopulmonary bypass, valve repair, or valve replacement. It operates outside the body and is attached to the heart during surgery. The Levitronix Centrimag is also being evaluated in clinical trials as a bridge support for patients whose hearts have gone into shock, while waiting for a transplant or a decision on treatment.
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