Intermountain Precision Genomics Expands a DNA-Based Test to Personalize Prescription Medications

RxMatch™ Comprehensive Panel

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Intermountain Precision Genomics Core Laboratory announced the expansion of RxMatch™, a pharmacogenomics service, to all Intermountain Healthcare providers. Originally launched as an antidepressant panel in September 2017, the new RxMatch™ Comprehensive Panel expands the gene targets from 36 to 97. 

PHARMA... what?

Pharmacogenomics, often abbreviated as PGx, is a relatively new advancement in the realm of personalized medicine. PGx blends medications (pharma), human genomics (through a DNA sample) and Rx, the symbol commonly used for prescription medications. PGx is the study of how genes affect a patient’s response to medication. 

Comprehensive and DNA Precise

The new RxMatch™ Comprehensive Panel includes opioids, statins, immunosuppressants, anti-depressants and many more. The results, powered by Coriell Life Sciences, seamlessly integrate genomic medicine into clinical care while managing the breadth of information that is obtained through genomic sequencing. David Loughmiller, Laboratory Manager for Intermountain Precision Genomics, said, “The objective of this project is to provide the most comprehensive and evidence-based information to the physician, thus decreasing the amount of time and money spent to achieve the correct medication.”

DNA Demystified

Patients supply a DNA sample using a cheek swab collected in their physician’s office. According to Tom Neuwerth, Intermountain Precision Genomics Lab Clinical Technology Consultant, “The DNA sample is extracted, assayed, and analyzed, in our CAP-accredited and CLIA-regulated clinical laboratory. Next, the results are used to guide proper dosage based on a patient’s specific DNA genotype. Small genetic variations impact how a patient metabolizes and responds to drugs. Our test helps ordering providers take the right medication, at the right dose, at the right time.”

Once the sample is received, a comprehensive report is available within about a week. One doctor who viewed an example of the report said, “We should have a report like this for all of our patients.” Intermountain Healthcare is widely recognized as a leader in transforming healthcare through high quality and sustainable costs.

Leaders at Intermountain Precision Genomics see RxMatch™ as a commitment to Intermountain Healthcare’s aspiration to “Become the most genetically advanced healthcare system in the world.” 

To request training, or to order an RxMatch™ Starter Kit for a physician office, please call (435) 251-5780 or visit www.Intermountain.com/RxMatch.