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Pancreas transplant

With some of the best pancreas transplant outcomes in the country, our team opens the door to better health for people with diabetes.

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New beginnings, expert care

When you need a pancreas transplant, you want to know your care is in the very best hands. Our board-certified surgeons and multidisciplinary care team have the skills and expertise you need to begin this next chapter of your health.

Advanced treatments

Our skilled surgical team performs the most complex transplant surgeries, including simultaneous pancreas/kidney transplant (SPK).

Unmatched expertise

Since 1983, we have performed over 300 transplants. Our comprehensive care consistently exceeds national success outcomes.

Shorter wait list

Our program has much shorter wait times than the national average.

How to apply for a pancreas transplant

Suppose you've been diagnosed with Type I Diabetes, and your doctor thinks you are a good candidate for a pancreas transplant. In that case, you can ask for a referral to our program for an evaluation. You can also refer yourself for a transplant evaluation.

You’ll be asked to provide the following information: 

  • Your most recent medical records
  • Your most recent lab work 
  • Any radiology reports
  • Reports of any surgery or procedures you have had (for example, colonoscopy, pap smear, mammogram, abdominal surgery, etc.)
  • Immunization records
  • Documentation of any psychiatric history
  • Dental work history
  • Proof of medical insurance

After this information is received, a transplant nephrologist will review your information. If you’re determined to be an appropriate candidate for transplant, we will schedule a clinic appointment for you. 

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Donate life

Become an organ donor

You have the power to save a life when you become an organ donor. Become a living organ donor today and provide one of your kidneys or a portion of your liver to someone in need. You can also register as an organ donor to make your organs available to those in need when you die.

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Frequently asked questions

Frequently asked questions regarding pancreas transplants

Scheduling your transplant
Before you undergo a transplant, we evaluate whether you're an appropriate candidate. Your first clinic visit will begin in the morning with a short orientation and proceed throughout the day. In this first visit, you will be seen by many of the professionals on our transplant team, including a transplant nephrologist, transplant surgeon, social worker, financial coordinator, transplant pharmacist, and dietician.

After your first clinic visit, our transplant team will clearly understand how to proceed with your transplant workup.

A majority of our patients will need additional testing to determine their suitability for transplant surgery. Some tests can be done during your initial visit; others can be done at your local hospital.

Testing & Evaluation
Next, we'll need to perform several pre-transplant tests that will help us determine your overall health status and identify potential problems before they occur. These tests also help us determine if transplantation is your best option.

Joining the waiting list
After completing your testing, your case is presented in a multidisciplinary selection meeting. Your options are discussed by surgeons, nephrologists, nurses, financial coordinators, social workers, and nutritionists. From here, a majority of patients are placed on the waiting list for a cadaveric pancreas donation.

When the time comes for surgery
When a donor pancreas becomes available, the coordinator will call you to get ready. Since this call could come at any time during the day or night, the transplant team should be able to reach you whether you are at home, at school, at work, or on vacation.

Please provide our transplant team with the phone numbers of family members and close friends. Do everything you can to make sure you can be contacted immediately.

When the Phone Call Comes
When that phone call comes, everything will seem like a blur. The coordinator will advise you when to be present at the transplant center. You must move quickly and get to the transplant center without delay. When a pancreas becomes available, there is a time limit!

At the Hospital
After admission, you will have a thorough physical examination, including more blood work, a chest x-ray, an EKG, dialysis, and possibly other tests. Unfortunately, surgery must be postponed in some cases. You will be sent home if:

  • You have an infection or have developed any other medical problem that would interfere with surgery or recovery
  • The donor pancreas shows signs of deterioration or poor function

If surgery is postponed, the transplant team can help you through the disappointment. This is only a temporary setback, and the search for a new pancreas will continue.

During your transplant surgery
Before entering the operating room, your anesthesiologist will review your medical history. Once they have completed this review, they will give you some medicine to help you relax. You will then be taken into the operating room. Once you're asleep, special I.V.s will be placed to help monitor your status during the surgery. This process takes between 30 and 60 minutes. 
 
After everything has been adequately prepared, your surgeon will begin your surgery. The surgery usually lasts between 2 and 3 hours. The surgery is generally performed through an incision close to your hip bone, measuring between 6 and 12 inches in length, depending on your size and the size of the kidney.

Life after your transplant surgery
If you don't have any complications following your transplant surgery, you should be ready to leave the hospital and head home within about a week. You will receive a schedule of follow-up clinic visits for lab tests and checkups. At these visits, your doctors will track your progress and detect potential complications as early as possible.

You should bring your medication list and surgery handbook to all follow-up visits. You will be given specific instructions for routine lab work or special tests that you might need.

Taking Care of Your New Pancreas
A donated organ is a beautiful gift that deserves to be taken care of. The most critical aspects of post-transplant care are listening to the advice of your doctors and properly taking your immuno-suppression medications. You'll need to take this medication for the rest of your life. This will significantly decrease the chance of rejection episodes, where your immune system attacks the new pancreas.

Modern medical advances — including immunosuppressant drugs that prevent rejection of the new pancreas — make pancreas transplant complications less and less common all the time. Patient and organ survival rates are high, and life expectancy rates are reasonable with the experience of the Intermountain Transplant Center team and your diligent efforts to care for your new pancreas until everyday life is once again possible.

Signs to Watch For
The primary concerns for your new pancreas involve infection and rejection. Your local physician can handle many problems, such as colds or flu, adjustment of your medications, and minor illnesses. You must take precautions and learn to watch for signs of infection and rejection that necessitate immediately notifying a local physician or transplant team. These include:

  • A fever that continues for more than two days 
  • A sudden increase in weight 
  • Pain, tenderness, or swelling of the new organ 
  • Ankle swelling 
  • Decrease in urine output 
  • Shortness of breath 
  • Change in glucose control
  • Most patients experiencing rejection have no symptoms, and the diagnosis is made solely based on blood tests. There are medications available to treat rejection.

  • Complete medical and surgical history: Determines additional tests that may need to be done.
  • Physical exam: Gives the doctor an overall picture of your condition(s).
  • Chest x-ray: Determines the health of your lungs and lower respiratory tract.
  • Electrocardiogram (EKG or E.C.G.): Determines how well your heart works and may reveal previously unsuspected heart damage.
  • Ultrasound with Doppler examination: Determines the quality of the iliac vessels.
  • Blood tests: Your blood count, blood and tissue type, blood chemistry, and immune system function will all be checked. Blood tests for certain infectious diseases will also be performed.
  • Pulmonary function test: You will breathe into a tube attached to a measuring device, revealing how well your lungs work and determining your blood's capacity to carry oxygen.
  • Upper gastrointestinal (G.I.) series: This will show whether or not your esophagus and stomach are disease-free.
  • Lower G.I. series: Ensures that you are free of intestinal abnormalities.
  • Renal function studies: Urine may be collected from you for 24 hours to determine if the kidneys are working correctly. Blood tests such as serum creatinine are also performed to measure kidney function.
  • Mammogram: X-ray of a woman's breast that can detect signs of breast cancer.
  • Pap smear: Cells collected from a woman's cervix are microscopically analyzed for signs of cancer.
  • Echocardiogram: Reveals any abnormalities in the heart.
  • Dental Evaluations: You need a dental checkup before being listed for transplant. Your dentist must tell us that your teeth and gums are healthy. You will also need to be checked by your dentist every year while you are waiting for your transplant.
  • Other tests: Any special tests or doctor visits that might be needed for the transplant workup.

Histocompatibility Laboratory Tests

  • Tissue Typing: This test is done on white blood cells. The white blood cells have unique "markers" that tell your "tissue type." You inherit tissue type from your mother and father. This test matches a kidney and pancreas to you.
  • Panel Reactive Antibody (P.R.A.): This test shows how active your immune system is. Getting a kidney is easier if your immune system is calm or measures 0%. Blood will be drawn at your dialysis center and sent to our laboratory. Your immune system may be active from blood transfusions, pregnancy, a previous transplant, or a current infection.
  • Crossmatch Testing: This test is done when a donor kidney is available. Your blood is mixed with the donor's blood. If there is no reaction (negative crossmatch), then you are "compatible" with the donor. If there is a reaction (positive crossmatch), then the kidney will not work for you because it is "incompatible."
  • Other Tests: The transplant doctors will ask for any special tests they think you need. For example, people with diabetes need more tests for their heart. Your transplant coordinator or dialysis doctor can help you arrange these tests.

Clinical Laboratory Tests

  • Blood Typing: There are four blood types: A, B, AB, and O. Every person has one of these types. The donor's blood type does not have to be the same, but it must be "compatible" with your blood type for you to receive their kidney or pancreas.
  • Viral Testing: We need to know if you have been exposed to hepatitis, cytomegalovirus (CMV), Epstein-Barr virus (EBV), or acquired immune deficiency syndrome (AIDS). We will test you for these at your clinic appointment.

Deceased pancreas donors did not have significant health problems that affected their pancreas—the donor's cause of death is usually an accident or sudden illness. Donors are expected to have good pancreas function. Pancreas donors are screened and may be excluded for positive H.I.V., hepatitis B, hepatitis C, or high-risk activity. Any high-risk donor characteristic will be discussed with you if you are a potential recipient for that donor's pancreas.

A pancreas from a deceased donor is allocated according to the United Network for Organ Sharing (U.N.O.S.) policy. Factors that contribute to the allocation process include ABO blood type, antibody levels, and waiting list time.

Suppose you are accepted as a transplant candidate. In that case, your name will be placed on the U.N.O.S. waiting list at Intermountain Medical Center. The pancreas transplant waiting list is a list of transplant candidates from around the country maintained by U.N.O.S. You will begin to build up waiting list time on the day you are listed — you will receive a letter telling you that date. Your nephrologist will continue to monitor your health while you are on the waiting list.

The average waiting time for a pancreas transplant at Intermountain Medical Center can vary from a few months to a year, depending on several different factors:

  • ABO blood type: the pancreas needs to come from a donor with a compatible blood type to yours. 
  • Your antibody level: this measures the strength of antibodies within your system. A high level of antibodies makes it more difficult to find a compatible donor who is compatible with you. 
  • The availability of an organ. 
 

When a donor organ becomes available, the transplant coordinator will call you. You will always have the right to decline an organ. If the surgeon determines the organ to be unusable, or if there is an incompatible crossmatch, you will be discharged home without the transplant. 

Certain conditions in the donor may affect the success of your pancreas transplant: the donor's history, the condition of the organ when it is received, and the potential risk of contracting infectious diseases or cancer if the doctor cannot detect them in the donated pancreas.

There are several potential complications associated with a Pancreas transplant surgery:

  • Blood clots
  • Bleeding 
  • Infection
  • Excess sugar in your blood (hyperglycemia) 
  • Urinary complications, including leaking or urinary tract infections 
  • Failure of the donated pancreas 
  • Rejection of the donated pancreas
  •  

Anti-Rejection Medication Side Effects
After a pancreas transplant, you'll take medications for the rest of your life to help prevent your body from rejecting the donor pancreas. These medications can cause a variety of side effects, including:

  • Bone thinning 
  • High cholesterol 
  • High blood pressure 
  • Skin sensitivity 
  • Puffiness 
  • Weight gain 
  • Swollen gums 
  • Acne 
  • Excessive hair growth

Helpful Links

Financial Resources

  • National Transplant Assistance Fund: Provides emergency one-time grants for patients who have had a transplant.
  • Social Security: Financial assistance for patients who will be disabled for at least a year and have enough "work credits." S.S.I. and S.S.D.I.
  • Cameron Siemers Foundation for Hope: Provides $5000 grant if you are between the ages of 18-28 and have been diagnosed with a life-threatening illness to be used to fulfill a dream, goal, or project that you take on to make a difference.

Medication Assistance

  • Rx Outreach: Provides deeply discounted mail-order medications; 90 and 180-day supplies for many medicines.
  • Rx Assist: Quick and easy-to-use database of all medication patient assistance programs. If you have trouble paying for a medication, you can do a quick search to find out if there might be an assistance program to help.

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